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Index of protein targets for approved drugs and nutraceuticals

The alphabetical index below lists the proteins defined in DrugBank as the targets of approved drugs and nutraceuticals.

Names shown in purple are human proteins.

Columns: drug; biotech drug; nutraceutical; T   no. of target structures in the PDB; TD   no. of target-drug structures.

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UniProt accession and id Protein name T TD
P49257 LMAN1_HUMAN ERGIC-53 protein - 1 - 7 -
P22413 ENPP1_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 2 - - 1 -
Q9GZT9 EGLN1_HUMAN Egl nine homolog 1 - - 1 17 -
Q96KS0 EGLN2_HUMAN Egl nine homolog 2 - - 1 - -
Q9H6Z9 EGLN3_HUMAN Egl nine homolog 3 - - 1 - -
P13551 EFG_THETH Elongation factor G 1 - - 19 -
Q9GZR5 ELOV4_HUMAN Elongation of very long chain fatty acids protein 4 - - 1 - -
P14625 ENPL_HUMAN Endoplasmin 1 - - 1 -
Q9UNN8 EPCR_HUMAN Endothelial protein C receptor - 1 - 3 -
P24530 EDNRB_HUMAN Endothelin B receptor 2 - - - -
P25101 EDNRA_HUMAN Endothelin-1 receptor 2 - - - -
P0A5Y6 INHA_MYCTU Enoyl-[acyl-carrier-protein] reductase [NADH] 2 - - 6 -
Q53I07 Q53I07_9HIV1 Envelope glycoprotein - 1 - - -
P68344 VGP3_EBVP3 Envelope glycoprotein GP340 1 - - - -
P03200 GP350_EBVB9 Envelope glycoprotein GP340/GP220 1 - - - -
P12724 ECP_HUMAN Eosinophil cationic protein 1 - - 7 -
P11678 PERE_HUMAN Eosinophil peroxidase - - 1 - -
P29317 EPHA2_HUMAN Ephrin type-A receptor 2 2 - - 21 -
P00533 EGFR_HUMAN Epidermal growth factor receptor 6 3 - 103 10
O75715 GPX5_HUMAN Epididymal secretory glutathione peroxidase - - 1 1 -
Q08345 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 1 - - 5 1
Ergosterol, Candida albicans 5 - - - -
P19235 EPOR_HUMAN Erythropoietin receptor 1 2 - 8 -
P14061 DHB1_HUMAN Estradiol 17-beta-dehydrogenase 1 - - 1 22 -
P37059 DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 - - 1 - -
P37058 DHB3_HUMAN Estradiol 17-beta-dehydrogenase 3 - - 1 - -
Q92506 DHB8_HUMAN Estradiol 17-beta-dehydrogenase 8 - - 1 4 -
P03372 ESR1_HUMAN Estrogen receptor 30 - 1 120 16
Q92731 ESR2_HUMAN Estrogen receptor beta 8 - - 29 3
P49888 ST1E1_HUMAN Estrogen sulfotransferase 1 - - 5 -
P62508 ERR3_HUMAN Estrogen-related receptor gamma 1 - - 17 -
P06864 BGA2_ECOLI Evolved beta-galactosidase subunit alpha 1 - - - -
P43003 EAA1_HUMAN Excitatory amino acid transporter 1 - - 1 - -
P43004 EAA2_HUMAN Excitatory amino acid transporter 2 - - 1 - -
P43005 EAA3_HUMAN Excitatory amino acid transporter 3 - - 2 - -
P48664 EAA4_HUMAN Excitatory amino acid transporter 4 - - 1 - -
O00341 EAA5_HUMAN Excitatory amino acid transporter 5 - - 1 - -
P41180 CASR_HUMAN Extracellular calcium-sensing receptor 1 - - - -
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