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Index of protein targets for approved drugs and nutraceuticals

The alphabetical index below lists the proteins defined in DrugBank as the targets of approved drugs and nutraceuticals.

Names shown in purple are human proteins.

Columns: drug; biotech drug; nutraceutical; T   no. of target structures in the PDB; TD   no. of target-drug structures.

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UniProt accession and id Protein name T TD
Q13131 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 1 - 2 - -
Q9Y478 AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 1 - 1 2 -
O43741 AAKB2_HUMAN 5'-AMP-activated protein kinase subunit beta-2 - - 1 11 -
P21589 5NTD_HUMAN 5'-nucleotidase 1 - - 6 -
Q5SNW5 Q5SNW5_HUMAN 5,10-methylenetetrahydrofolate reductase - - 1 - -
P22557 HEM0_HUMAN 5-aminolevulinate synthase, erythroid-specific, mitochondrial - - 1 - -
P13196 HEM1_HUMAN 5-aminolevulinate synthase, nonspecific, mitochondrial - - 1 - -
P08908 5HT1A_HUMAN 5-hydroxytryptamine 1A receptor 45 - - - -
P28222 5HT1B_HUMAN 5-hydroxytryptamine 1B receptor 27 - - 3 -
P28221 5HT1D_HUMAN 5-hydroxytryptamine 1D receptor 24 - - - -
P28566 5HT1E_HUMAN 5-hydroxytryptamine 1E receptor 6 - - - -
P30939 5HT1F_HUMAN 5-hydroxytryptamine 1F receptor 5 - - - -
P28223 5HT2A_HUMAN 5-hydroxytryptamine 2A receptor 61 - - - -
P41595 5HT2B_HUMAN 5-hydroxytryptamine 2B receptor 16 - - 2 -
P28335 5HT2C_HUMAN 5-hydroxytryptamine 2C receptor 35 - - - -
P46098 5HT3A_HUMAN 5-hydroxytryptamine 3 receptor 18 - - - -
Q13639 5HT4R_HUMAN 5-hydroxytryptamine 4 receptor 4 - - - -
P50406 5HT6R_HUMAN 5-hydroxytryptamine 6 receptor 8 - - - -
P34969 5HT7R_HUMAN 5-hydroxytryptamine 7 receptor 14 - - - -
P47898 5HT5A_HUMAN 5-hydroxytryptamine receptor 5A 1 - - - -
O14841 OPLA_HUMAN 5-oxoprolinase - - 1 - -
P0A7J6 RL10_SHIFL 50S ribosomal protein L10 5 - - - -
P0ADY7 RL16_ECOLI 50S ribosomal protein L16 1 - - 107 -
P20276 RL2_HALMA 50S ribosomal protein L2 1 - - 67 -
P61177 RL22_ECO57 50S ribosomal protein L22 3 - - 1 -
Q9A1X4 RL3_STRP1 50S ribosomal protein L3 1 - - - -
P49228 RL32_DEIRA 50S ribosomal protein L32 1 - - 28 -
P44345 RL4_HAEIN 50S ribosomal protein L4 1 - - - -
P60723 RL4_ECOLI 50S ribosomal protein L4 (RL4_ECOLI) 1 - - 106 -
P60725 RL4_ECO57 50S ribosomal protein L4 (RL4_ECO57) 2 - - - -
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