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Index of protein targets for approved drugs and nutraceuticals

The alphabetical index below lists the proteins defined in DrugBank as the targets of approved drugs and nutraceuticals.

Names shown in purple are human proteins.

Columns: drug; biotech drug; nutraceutical; T   no. of target structures in the PDB; TD   no. of target-drug structures.

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B

UniProt accession and id Protein name T TD
P82251 BAT1_HUMAN B(0,+)-type amino acid transporter 1 - - 1 - -
P15056 BRAF_HUMAN B-Raf proto-oncogene serine/threonine-protein kinase 4 - - 41 2
P11836 CD20_HUMAN B-lymphocyte antigen CD20 - 3 - 5 -
P30411 BKRB2_HUMAN B2 bradykinin receptor 1 - - - -
O60427 FADS1_HUMAN BC269730_2 - - 2 - -
A9UF02 A9UF02_HUMAN BCR/ABL fusion protein isoform X9 1 - - - -
Q16620 NTRK2_HUMAN BDNF/NT-3 growth factors receptor 1 - - 7 -
Bacterial cell wall 4 - - - -
P98160 PGBM_HUMAN Basement membrane-specific heparan sulfate proteoglycan core protein - 1 - 2 -
P11362 FGFR1_HUMAN Basic fibroblast growth factor receptor 1 3 1 - 34 -
P09619 PGFRB_HUMAN Beta platelet-derived growth factor receptor 6 1 - 6 -
P08588 ADRB1_HUMAN Beta-1 adrenergic receptor 40 - 1 1 -
P15291 B4GT1_HUMAN Beta-1,4-galactosyltransferase 1 - - 1 16 12
O60909 B4GT2_HUMAN Beta-1,4-galactosyltransferase 2 - - 1 - -
O60512 B4GT3_HUMAN Beta-1,4-galactosyltransferase 3 - - 1 - -
O60513 B4GT4_HUMAN Beta-1,4-galactosyltransferase 4 - - 1 - -
P07550 ADRB2_HUMAN Beta-2 adrenergic receptor 44 - 1 16 -
P13945 ADRB3_HUMAN Beta-3 adrenergic receptor 10 - 1 1 -
P25098 ARBK1_HUMAN Beta-adrenergic receptor kinase 1 - - 1 6 -
P35626 ARBK2_HUMAN Beta-adrenergic receptor kinase 2 - - 1 - -
P00811 AMPC_ECOLI Beta-lactamase 2 - - 93 1
P00807 BLAC_STAAU Beta-lactamase (BLAC_STAAU) 2 - - 16 -
P05193 AMPC_CITFR Beta-lactamase (AMPC_CITFR) 1 - - 1 -
P0AD63 BLA1_ECOLX Beta-lactamase SHV-1 precursor 1 - - - -
P62594 BLAT_SALTI Beta-lactamase TEM 1 - - - -
P01138 NGF_HUMAN Beta-nerve growth factor 1 - - 5 -
Q93088 BHMT1_HUMAN Betaine--homocysteine S-methyltransferase 1 - - 1 3 -
Q9H2M3 BHMT2_HUMAN Betaine--homocysteine S-methyltransferase 2 - - 1 - -
P07814 SYEP_HUMAN Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase - - 2 5 -
P13922 DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase 3 - - 10 1
P13995 MTDC_HUMAN Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial - - 2 1 -
P31939 PUR9_HUMAN Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase 1 - 1 3 -
Q14032 BAAT_HUMAN Bile acid CoA:amino acid N-acyltransferase - - 1 - -
Q96RI1 NR1H4_HUMAN Bile acid receptor 1 - - 24 -
Bile acids 3 - - - -
O95342 ABCBB_HUMAN Bile salt export pump 1 - 1 - -
P53004 BIEA_HUMAN Biliverdin reductase A - - 1 1 -
P50747 BPL1_HUMAN Biotin--protein ligase - - 1 - -
P13727 PRG2_HUMAN Bone-marrow proteoglycan - 1 - 2 -
P54687 BCAT1_HUMAN Branched-chain-amino-acid aminotransferase, cytosolic - - 4 4 -
O15382 BCAT2_HUMAN Branched-chain-amino-acid aminotransferase, mitochondrial - - 3 11 -
P11274 BCR_HUMAN Breakpoint cluster region protein 2 - - 2 -
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