Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception..
There are currently no structures for this UniProt code in
Schematic diagram of Pfam domains in target sequence
Sequence length: 638 a.a.
targeting this protein
for this target protein: