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DrugBank target: P18405
3-oxo-5-alpha-steroid 4-dehydrogenase 1
SR type 1, Steroid 5-alpha-reductase 1, S5AR 1.
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology..
A 3-oxo-5-alpha-steroid + NADP(+) = a 3-oxo- Delta(4)-steroid + NADPH.
There are currently
structures for this UniProt code in the PDB.
Approved drugs targeting this protein
drugs for this target protein:
PDB structures containing this molecule although none are bound to the above target protein.
PDB structure containing this molecule but it is not bound to the above target protein.
structures of this molecule in the PDB.
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