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DrugBank target: P48039

DrugBank target: P48039 (MTR1A_HUMAN)

Melatonin receptor type 1A

Mel-1A-R, Mel1a receptor.

Function

High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity..

Structures

There are currently no structures for this UniProt code in the PDB.

Key:  

Approved drugs / nutraceuticals targeting this protein

The DrugBank database identifies 2 drugs and and 1 nutraceutical for this target protein:

 

 
Generic name: DB06594 agomelatine
Formula: C15H17No2
Structure: There are no structures of this molecule in the PDB.
 
Generic name: DB00980 ramelteon
Formula: C16H21No2
Structure: There are no structures of this molecule in the PDB.
Generic name: DB01065 melatonin
ML1
Formula: C13H16N2O2
Structure: There are 3 PDB structures containing this molecule although none are bound to the above target protein.

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