There are 8 structures corresponding
to this UniProt sequence in the PDB. Click the orange, plus icon above
for a list.
D(2) dopamine receptor
Dopamine D2 receptor.
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity)..
Dystonia 11 (DYT11) [MIM:159900]: A myoclonic dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. DYT11 is characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Inheritance is autosomal dominant. The age of onset, pattern of body involvement, presence of myoclonus and response to alcohol are all variable. Note=The gene represented in this entry may be involved in disease pathogenesis. DRD2 mutations in myoclonic dystonia patients are rare, and their contribution to disease phenotype is unclear (PubMed:10716258).
Schematic diagram of Pfam domains in target sequence
plus wiring diagrams of PDB structures