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DrugBank target: Q9ULA0

DrugBank target: Q9ULA0 (DNPEP_HUMAN)     

Example structure of target: 4dyo

( There is one structure corresponding to this UniProt sequence in the PDB. )

Aspartyl aminopeptidase

Function

Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism..

Enzyme

3.4.11.21   [EC->PDB]   [IntEnz]   [ExPASy]   [KEGG]  

Catalytic activity

Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.

Schematic diagram of Pfam domains in target sequence plus wiring diagram of PDB structure of target.

4dyo

Key:    PfamA domain

Sequence length: 474 a.a.

Approved nutraceuticals targeting this protein

The DrugBank database identifies 1 nutraceutical for this target protein:

 

Generic name: DB00142 l-glutamic acid
GGL
Formula: C5H9No4
Structure: There are 9 PDB structures containing this molecule although none are bound to the above target protein.

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