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DrugBank target: P34972

DrugBank target: P34972 (CNR2_HUMAN)     

Example structure of target: 2ki9

( There is one structure corresponding to this UniProt sequence in the PDB. )

Cannabinoid receptor 2

CX5, CB-2, CB2, hCB2.

Function

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis..

Schematic diagram of Pfam domains in target sequence plus wiring diagrams of PDB structures of target.

2ki9
2ki9

Key:    PfamA domain

Sequence length: 359 a.a.

Approved drugs targeting this protein

The DrugBank database identifies 2 drugs for this target protein:

 

 
Generic name: DB00486 nabilone
Formula: C24H36O3
Structure: There are no structures of this molecule in the PDB.
Generic name: DB00470 dronabinol
TCI
Formula: C21H30O2
Structure: There is one PDB structure containing this molecule but it is not bound to the above target protein.

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