spacer
spacer

Search 

DrugBank target: P53608

DrugBank target: P53608 (ARGI_BACCD)     

Example drug-target structure: 2cev

( There are 5 structures corresponding to this UniProt sequence in the PDB. Click the orange, plus icon above for a list. )

Arginase

Function

Controls arginine catabolism..

Enzyme

3.5.3.1   [EC->PDB]   [IntEnz]   [ExPASy]   [KEGG]  

Catalytic activity

L-arginine + H(2)O = L-ornithine + urea.

Schematic diagram of Pfam domains in target sequence plus wiring diagram of PDB structure containing drug molecule

2cev

Key:    PfamA domain  Secondary structure  Bound drug molecule

Sequence length: 298 a.a.

Approved drugs targeting this protein

The DrugBank database identifies 1 drug for this target protein:

 

Generic name: DB00536 guanidine
GAI
Formula: Ch5N3
Structure: There are 53 PDB structures containing this molecule of which 3 are bound to the above target protein.

  spacer

spacer