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DrugBank target: O14561

DrugBank target: O14561 (ACPM_HUMAN)     

Example structure of target: 2dnw

( There is one structure corresponding to this UniProt sequence in the PDB. )

Acyl carrier protein, mitochondrial

CI-SDAP, NADH-ubiquinone oxidoreductase 9.6 kDa subunit, ACP.

Function

Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity)..

Schematic diagram of Pfam domains in target sequence plus wiring diagram of PDB structure of target.

2dnw

Key:    PfamA domain  PfamB domain

Sequence length: 155 a.a.

Approved nutraceuticals targeting this protein

The DrugBank database identifies 1 nutraceutical for this target protein:

 

Generic name: DB00157 nadh
NAI
Formula: C21H29N7O14P2
Structure: There are 137 PDB structures containing this molecule although none are bound to the above target protein.

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