There are 2 structures corresponding
to this UniProt sequence in the PDB. Click the orange, plus icon above
for a list.
Neuronal acetylcholine receptor subunit alpha-4
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions..
Epilepsy, nocturnal frontal lobe, 1 (ENFL1) [MIM:600513]: An autosomal dominant focal epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements. Note=The disease is caused by mutations affecting the gene represented in this entry.
Schematic diagram of Pfam domains in target sequence
plus wiring diagrams of PDB structures