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DrugBank target: P30542

DrugBank target: P30542 (AA1R_HUMAN)     

Adenosine receptor A1

Function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase..

Structures

There are currently no structures for this UniProt code in the PDB.

Schematic diagram of Pfam domains in target sequence

Key:    PfamA domain

Sequence length: 326 a.a.

Approved drugs / biotech drugs targeting this protein

The DrugBank database identifies 9 drugs and 1 biotech drug for this target protein:

 

Generic name: DB01412 theobromine
37T
Formula: C7H8N4O2
Structure: There is one PDB structure containing this molecule but it is not bound to the above target protein.
Generic name: DB00806 pentoxifylline
PNX
Formula: C13H18N4O3
Structure: There are 4 PDB structures containing this molecule although none are bound to the above target protein.
Generic name: DB00640 adenosine
ADN
Formula: C10H13N5O4
Structure: There are 122 PDB structures containing this molecule although none are bound to the above target protein.

 

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Generic name: DB04932 defibrotide
Formula:
Structure: There are no structures of this molecule in the PDB.
Generic name: DB00201 caffeine
CFF
Formula: C8H10N4O2
Structure: There are 10 PDB structures containing this molecule although none are bound to the above target protein.
 
Generic name: DB01303 oxtriphylline
Formula: C12H21N5O3
Structure: There are no structures of this molecule in the PDB.
 
Generic name: DB01223 aminophylline
Formula: C16H24N10O4
Structure: There are no structures of this molecule in the PDB.
Generic name: DB00651 dyphylline
X0T
Formula: C10H14N4O4
Structure: There is one PDB structure containing this molecule but it is not bound to the above target protein.
Generic name: DB00996 gabapentin
GBN
Formula: C9H17No2
Structure: There are 4 PDB structures containing this molecule although none are bound to the above target protein.
Generic name: DB00277 theophylline
TEP
Formula: C7H8N4O2
Structure: There are 6 PDB structures containing this molecule although none are bound to the above target protein.

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