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Drug/nutraceutical targets classed as GO:0010467 - : gene expression

Targets
Structure(s) of protein in PDB   No structures   Protein names shown in purple are human proteins.
Drugs
Target-drug structure(s) in PDB   Drug structure(s) in PDB   No structures.
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Alphabetical listing of protein targets and their drugs

  1.  
Asparaginyl-tRNA synthetase, cytoplasmic O43776/SYNC_HUMAN
  Drugs:  l-asparagine.
  2.  
Aspartyl-tRNA synthetase, cytoplasmic P14868/SYDC_HUMAN
  Drugs:  l-aspartic acid.
  3.  
Aspartyl-tRNA synthetase, mitochondrial Q6PI48/SYDM_HUMAN
  Drugs:  l-aspartic acid.
  4.  
Cysteinyl-tRNA synthetase, cytoplasmic P49589/SYCC_HUMAN
  Drugs:  l-cysteine.
  5.  
Estrogen receptor P03372/ESR1_HUMAN
  Drugs:  chlorotrianisene, fulvestrant, estradiol, estrone, diethylstilbestrol, fluoxymesterone, tamoxifen, allylestrenol, levonorgestrel, estriol, desogestrel, medroxyprogesterone, progesterone, etonogestrel, ospemifene, ethinyl estradiol, conjugated estrogens, ethynodiol diacetate, naloxone, dienestrol, danazol, estramustine, raloxifene, clomifene, norgestimate, estropipate, toremifene, melatonin, trilostane, mestranol, quinestrol.
  6.  
Estrogen-related receptor gamma P62508/ERR3_HUMAN
  Drugs:  diethylstilbestrol.
  7.  
Glucocorticoid receptor P04150/GCR_HUMAN
  Drugs:  beclometasone dipropionate, halobetasol propionate, desoximetasone, fluticasone furoate, clobetasol, methylprednisolone, flumethasone pivalate, loteprednol, flunisolide, prednisone, fluticasone propionate, hydrocortamate, mifepristone, fluocinonide, prednicarbate, alclometasone, paramethasone, fluocinolone acetonide, prednisolone, ciclesonide, fluoxymesterone, amcinonide, hydrocortisone, flurandrenolide, diflorasone, triamcinolone, betamethasone, budesonide, dexamethasone, cortisone acetate, rimexolone, mometasone, megestrol, medrysone, desonide, fluorometholone, clocortolone, fludrocortisone, difluprednate.
  8.  
Histidyl-tRNA synthetase, cytoplasmic P12081/SYHC_HUMAN
  Drugs:  l-histidine.
  9.  
Isoleucyl-tRNA synthetase, mitochondrial Q9NSE4/SYIM_HUMAN
  Drugs:  l-isoleucine.
  10.  
Leucyl-tRNA synthetase, cytoplasmic Q9P2J5/SYLC_HUMAN
  Drugs:  l-leucine.
  11.  
Mineralocorticoid receptor P08235/MCR_HUMAN
  Drugs:  progesterone, spironolactone, fluticasone propionate, drospirenone, nimodipine, eplerenone, felodipine, fludrocortisone.
  12.  
Nuclear receptor subfamily 1 group I member 2 O75469/NR1I2_HUMAN
  Drugs:  estradiol, erlotinib, rilpivirine, rifaximin, ethinyl estradiol, paclitaxel, rifampin, vitamin e.
  13.  
Phenylalanyl-tRNA synthetase alpha chain Q9Y285/SYFA_HUMAN
  Drugs:  l-phenylalanine.
  14.  
Phenylalanyl-tRNA synthetase beta chain Q9NSD9/SYFB_HUMAN
  Drugs:  l-phenylalanine.
  15.  
Phenylalanyl-tRNA synthetase, mitochondrial O95363/SYFM_HUMAN
  Drugs:  l-phenylalanine.
  16.  
Plasminogen activator inhibitor 1 P05121/PAI1_HUMAN
  Drugs:  reteplase, alteplase, urokinase, drotrecogin alfa, tenecteplase, anistreplase.
  17.  
Probable alanyl-tRNA synthetase, mitochondrial Q5JTZ9/SYAM_HUMAN
  Drugs:  l-alanine.
  18.  
Probable asparaginyl-tRNA synthetase, mitochondrial Q96I59/SYNM_HUMAN
  Drugs:  l-asparagine.
  19.  
Probable cysteinyl-tRNA synthetase, mitochondrial Q9HA77/SYCM_HUMAN
  Drugs:  l-cysteine.
  20.  
Probable glutamyl-tRNA synthetase, mitochondrial Q5JPH6/SYEM_HUMAN
  Drugs:  l-glutamic acid.

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