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Drug/nutraceutical targets classed as GO:0006955 - : immune response

Targets
Structure(s) of protein in PDB   No structures   Protein names shown in purple are human proteins.
Drugs
Target-drug structure(s) in PDB   Drug structure(s) in PDB   No structures.
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Alphabetical listing of protein targets and their drugs

  1.  
Cannabinoid receptor 2 P34972/CNR2_HUMAN
  Drugs:  nabilone, dronabinol.
  2.  
Cysteinyl leukotriene receptor 2 Q9NS75/CLTR2_HUMAN
  Drugs:  nedocromil.
  3.  
Cytochrome P450 11B1, mitochondrial P15538/C11B1_HUMAN
  Drugs:  metyrapone, mitotane.
  4.  
Delta-type opioid receptor P41143/OPRD_HUMAN
  Drugs:  codeine, naltrexone, levorphanol, oxycodone, nalbuphine, hydrocodone, sufentanil, diphenoxylate, propoxyphene, alvimopan, tapentadol, hydromorphone, remifentanil, tramadol, methadone, oxymorphone, morphine, heroin, amitriptyline, fentanyl, naloxone, buprenorphine, loperamide, butorphanol.
  5.  
Endothelial protein C receptor Q9UNN8/EPCR_HUMAN
  Drugs:  drotrecogin alfa.
  6.  
Ferritin heavy chain P02794/FRIH_HUMAN
  Drugs:  iron dextran.
  7.  
High affinity immunoglobulin epsilon receptor subunit beta Q01362/FCERB_HUMAN
  Drugs:  omalizumab.
  8.  
Ig kappa chain V-II region RPMI 6410 P06310/KV206_HUMAN
  Drugs:  fluorescein.
  9.  
Inhibitor of nuclear factor kappa-B kinase subunit alpha O15111/IKKA_HUMAN
  Drugs:  aminosalicylic acid, mesalazine, sulfasalazine.
  10.  
Insulin-like growth factor 1 receptor P08069/IGF1R_HUMAN
  Drugs:  mecasermin, insulin glargine, insulin, porcine, insulin lispro.
  11.  
Interleukin-1 alpha P01583/IL1A_HUMAN
  Drugs:  rilonacept.
  12.  
Interleukin-1 beta P01584/IL1B_HUMAN
  Drugs:  gallium nitrate, rilonacept, canakinumab, minocycline.
  13.  
Interleukin-1 receptor antagonist protein P18510/IL1RA_HUMAN
  Drugs:  rilonacept.
  14.  
Interleukin-1 receptor type I P14778/IL1R1_HUMAN
  Drugs:  anakinra.
  15.  
Interleukin-2 receptor alpha chain P01589/IL2RA_HUMAN
  Drugs:  denileukin diftitox, basiliximab, daclizumab, aldesleukin.
  16.  
Interleukin-3 P08700/IL3_HUMAN
  Drugs:  amlexanox.
  17.  
Interleukin-5 P05113/IL5_HUMAN
  Drugs:  pranlukast.
  18.  
Interleukin-6 P05231/IL6_HUMAN
  Drugs:  ginseng.
  19.  
Kappa-type opioid receptor P41145/OPRK_HUMAN
  Drugs:  tapentadol, hydromorphone, sufentanil, heroin, menthol, nalbuphine, methylnaltrexone, pentazocine, alvimopan, tramadol, remifentanil, fentanyl, levorphanol, morphine, butorphanol, loperamide, amitriptyline, codeine, propoxyphene, dezocine, buprenorphine, meperidine, oxycodone, naltrexone, naloxone, mirtazapine.
  20.  
Low affinity immunoglobulin gamma Fc region receptor II-c P31995/FCG2C_HUMAN
  Drugs:  alemtuzumab, tositumomab, trastuzumab, basiliximab, abciximab, adalimumab, rituximab, gemtuzumab ozogamicin, cetuximab, natalizumab, ibritumomab, bevacizumab, efalizumab, palivizumab, alefacept, daclizumab, muromonab, intravenous immunoglobulin, etanercept.

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