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DB08816 : ticagrelor

Approved drug ticagrelor ... 1 target DB08816

Generic name: ticagrelor
 
Brand name(s): brilique, possia.
Formula: C23H28F2N6O4S
IUPAC Formula: (1s,2s,3r,5s)-3-(7-{[(1r,2s)-2-(3,4-Difluorophenyl)cyclopropyl]amino}-5-(Propylsulfanyl)-3h-
[1,2,3]triazolo[4,5-D]pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)cyclopentane-1,2-Diol

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: Q9H244 (P2Y12_HUMAN)  -  P2Y purinoceptor 12
UniProt id: Q9H244    341 a.a.  
1. 1t78 A     337 a.a. 336   Theor. model
  2. 1vz1 A     337 a.a. 336   Theor. model
  3. 1y9c A     302 a.a. 302   Theor. model
There are no PDB entries containing ticagrelor bound to this target protein, although there are 6 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

Structure selection

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