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DB06716 : fospropofol

Approved drug fospropofol ... 2 targets DB06716

Generic name: fospropofol
 
Brand name(s): aquavan, lusedra.
Formula: C13H21O5P
IUPAC Formula: [2,6-Bis(propan-2-Yl)phenoxymethoxy]phosphonic acid

2
There are 2 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P47870 (GBRB2_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit beta-2
UniProt id: P47870    512 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P28472 (GBRB3_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit beta-3
UniProt id: P28472    472 a.a.  
4cof A,B,C,D,E     340 a.a. 309   X-ray 2.97 Å
There are no PDB entries containing fospropofol bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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