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DB06267 : udenafil

Approved drug udenafil ... 1 target DB06267

Generic name: udenafil
 
Brand name(s): zydena.
Formula: C25H36N6O4S
IUPAC Formula: 3-{1-Methyl-7-Oxo-3-Propyl-1h,4h,7h-Pyrazolo[4,3-D]pyrimidin-5-Yl}-N-[2-(1-Methylpyrrolidin-2-
Yl)ethyl]-4-Propoxybenzene-1-Sulfonamide

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: O76074 (PDE5A_HUMAN)  -  CGMP-specific 3',5'-cyclic phosphodiesterase
UniProt id: O76074    874 a.a.  
1. 3lfv A,B     391 a.a. 380   X-ray 2.80 Å
  2. 3mf0 A,B     378 a.a. 376   X-ray 3.10 Å
  3. 2h44 A     326 a.a. 326   X-ray 1.80 Å
  4. 2h42 A,B,C     326 a.a. 326   X-ray 2.30 Å
  5. 1udt A     313 a.a. 313   X-ray 2.30 Å
   more ...
There are no PDB entries containing udenafil bound to this target protein, although there are 34 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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