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DB06228 : rivaroxaban

Approved drug rivaroxaban ... 1 target DB06228

Generic name: rivaroxaban PDB Het Group: RIV
 
1 structure in PDB
Brand name(s): xarelto.
Formula: C19H18Cln3O5S
IUPAC Formula: 5-Chloro-N-{[(5s)-2-Oxo-3-[4-(3-Oxomorpholin-4-Yl)phenyl]-1,3-Oxazolidin-5-Yl]methyl}thiophene-2-
Carboxamide
PDB name: 5-Chloro-N-({(5s)-2-Oxo-3-[4-(3-Oxomorpholin-4-Yl)phenyl]-1,3-Oxazolidin-5-Yl}methyl)thiophene-2-
Carboxamide

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
 2 
There are 2 PDB structures of the drug molecule bound to its target protein.
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Target proteins

DrugBank drug Target 1:   UniProt id: P00742 (FA10_HUMAN)  -  Coagulation factor X
UniProt id: P00742    487 a.a.  
2w26 A   234 a.a. 234   X-ray 2.08 Å
The PDB contains 2 entries of rivaroxaban bound to this target protein and 128 entries of this target protein in all (click on orange, plus icon for list).

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

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