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DB06203 : alogliptin

Approved drug alogliptin ... 1 target DB06203

Generic name: alogliptin PDB Het Group: T22
 
1 structure in PDB
Brand name(s): nesina.
Formula: C18H21N5O2
IUPAC Formula: 2-({6-[(3r)-3-Aminopiperidin-1-Yl]-3-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-1-
Yl}methyl)benzonitrile
PDB name: 2-({6-[(3r)-3-Aminopiperidin-1-Yl]-3-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-
Yl}methyl)benzonitrile

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
 1 
There is 1 PDB structure of the drug molecule bound to its target protein.
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Target proteins

DrugBank drug Target 1:   UniProt id: P27487 (DPP4_HUMAN)  -  Dipeptidyl peptidase 4
UniProt id: P27487    765 a.a.  
3g0b A,B,C,D   727 a.a. 727   X-ray 2.25 Å
The PDB contains 1 entry of alogliptin bound to this target protein and 89 entries of this target protein in all (click on orange, plus icon for list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

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