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DB06151 : acetylcysteine

Approved drug acetylcysteine ... 1 target DB06151

Generic name: acetylcysteine PDB Het Group: SC2
 
3 structures in PDB
Brand name(s): acetadote, fluimucil, lysox, mucolysin, mucomyst, parvolex.
Formula: C5H9No3S
IUPAC Formula: (2r)-2-Acetamido-3-Sulfanylpropanoic acid
PDB name: N-Acetyl-L-Cysteine

1
There is 1 target protein defined in DrugBank for this drug.
 2 
There are 2 PDB structures containing the drug molecule bound to a protein that is not specified as a target.
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Target proteins

DrugBank drug Target 1:   Bacterial outer membrane
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:  

 

Other proteins with acetylcysteine bound in the PDB

There are 2 "non-target" proteins in the PDB containing the acetylcysteine molecule bound. That is, the UniProt code for the proteins is missing or does not match the drug target above.

Protein 1:   UniProt id: P61626 ()  -  Lysozyme C OS=Homo sapiens GN=LYZ PE=1 SV=1
UniProt id: P61626    147 a.a.  
207l A   130 a.a. 129   X-ray 1.80 Å
The PDB contains 1 entry of acetylcysteine bound to this protein
Protein 2:   UniProt id: Q15485 ()  -  Ficolin-2 OS=Homo sapiens GN=FCN2 PE=1 SV=2
UniProt id: Q15485    312 a.a.  
2j2p A,B,C,D,...   214 a.a. 212   X-ray 2.80 Å
The PDB contains 1 entry of acetylcysteine bound to this protein

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

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