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DB04932 : defibrotide

Approved biotech drug defibrotide ... 3 targets DB04932

Generic name: defibrotide
No image
 
Brand name(s): dasovas, noravid, prociclide.
Formula: None
IUPAC Formula: None

3
There are 3 target proteins defined in DrugBank for this biotech drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank biotech drug Target 1:   UniProt id: P30542 (AA1R_HUMAN)  -  Adenosine A1 receptor
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank biotech drug Target 2:   UniProt id: P29274 (AA2AR_HUMAN)  -  Adenosine A2a receptor
UniProt id: P29274    411 a.a.  
1. 1upe A     304 a.a. 303   Theor. model
  2. 2ydv A     315 a.a. 302   X-ray 2.60 Å
  3. 3vg9 A     297 a.a. 297   X-ray 2.70 Å
  4. 2ydo A     309 a.a. 297   X-ray 3.00 Å
  5. 3vga A     296 a.a. 296   X-ray 3.10 Å
   more ...
There are no PDB entries containing defibrotide bound to this target protein, although there are 14 entries of the target protein (click the orange, plus icon for a list).
DrugBank biotech drug Target 3:   UniProt id: P29275 (AA2BR_HUMAN)  -  Adenosine A2b receptor
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

 

 

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