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DB04894 : vapreotide

Approved drug vapreotide ... 3 targets DB04894

Generic name: vapreotide
 
Brand name(s): sanvar, sanvar ir.
Formula: C57H70N12O9S2
IUPAC Formula: 2-Amino-N-[10-(4-Aminobutyl)-4-{[1-Carbamoyl-2-(1h-Indol-2-Yl)ethyl]carbamoyl}-16-[(4-
Hydroxyphenyl)methyl]-13-(1h-Indol-3-Ylmethyl)-6,9,12,15,18-Pentaoxo-7-(Propan-2-Yl)-1,2-Dithia-
5,8,11,14,17-Pentaazacycloicosan-19-Yl]-3-Phenylpropanamide

3
There are 3 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
Links  
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KEGG drug
PubChem
Information  
Pharmacology
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Target proteins

DrugBank drug Target 1:   UniProt id: P30874 (SSR2_HUMAN)  -  Somatostatin receptor type 2
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P35346 (SSR5_HUMAN)  -  Somatostatin receptor type 5
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: P25103 (NK1R_HUMAN)  -  Substance-P receptor
UniProt id: P25103    406 a.a.  
1. 2ks9 A     363 a.a. 363   NMR  
  2. 2ksa A     363 a.a. 363   NMR  
  3. 2ksb A     363 a.a. 363   NMR  
There are no PDB entries containing vapreotide bound to this target protein, although there are 3 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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