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DB04838 : cyclandelate

Approved drug cyclandelate ... 2 targets DB04838

Generic name: cyclandelate
 
Brand name(s): arto-espasmol, capilan, ciclospasmol, clandilon, cyclergine, cyclobral, cyclolyt, cyclomandol, cyclospasmol, dilatan, natil, novodil, perebral, saiclate, sancyclan, sepyron, spasmione, spasmocyclon, spasmocyclone, vasodyl.
Formula: C17H24O3
IUPAC Formula: 3,3,5-Trimethylcyclohexyl 2-Hydroxy-2-Phenylacetate

2
There are 2 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P54289 (CA2D1_HUMAN)  -  Voltage-dependent calcium channel subunit alpha-2/delta-1
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P23141 (EST1_HUMAN)  -  Liver carboxylesterase 1
UniProt id: P23141    566 a.a.  
1. 2h7c A,B,C,D,...     532 a.a. 532   X-ray 2.00 Å
  2. 1mx1 A,B,C,D,...     532 a.a. 532   X-ray 2.40 Å
  3. 2hrq A,B,C,D,...     532 a.a. 532   X-ray 2.70 Å
  4. 2hrr A,B,C     532 a.a. 532   X-ray 2.70 Å
  5. 1mx5 A,B,C,D,...     532 a.a. 532   X-ray 2.80 Å
   more ...
There are no PDB entries containing cyclandelate bound to this target protein, although there are 15 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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