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DB01364 : ephedrine

Approved drug ephedrine ... 4 targets DB01364

Generic name: ephedrine
 
Brand name(s): none.
Formula: C10H15No
IUPAC Formula: (1r,2s)-2-(Methylamino)-1-Phenylpropan-1-Ol

4
There are 4 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P23975 (SC6A2_HUMAN)  -  Sodium-dependent noradrenaline transporter
UniProt id: P23975    617 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P35348 (ADA1A_HUMAN)  -  Alpha-1A adrenergic receptor
UniProt id: P35348    466 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: Q05940 (VMAT2_HUMAN)  -  Synaptic vesicular amine transporter
UniProt id: Q05940    514 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 4:   UniProt id: P22303 (ACES_HUMAN)  -  Acetylcholinesterase
UniProt id: P22303    613 a.a.  
1. 4bdt A     563 a.a. 563   X-ray 3.10 Å
  2. 1clj       538 a.a. 538   Theor. model
  3. 1puv A     538 a.a. 538   Theor. model
  4. 1puw A     538 a.a. 538   Theor. model
  5. 2x8b A     536 a.a. 535   X-ray 2.95 Å
   more ...
There are no PDB entries containing ephedrine bound to this target protein, although there are 16 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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