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DB01320 : fosphenytoin

Approved drug fosphenytoin ... 1 target DB01320

Generic name: fosphenytoin
 
Brand name(s): cerebyx, prodilantin.
Formula: C16H15N2O6P
IUPAC Formula: [(2,5-Dioxo-4,4-Diphenylimidazolidin-1-Yl)methoxy]phosphonic acid

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: Q14524 (SCN5A_HUMAN)  -  Sodium channel protein type 5 subunit alpha
UniProt id: Q14524    2015 a.a.  
1. 4dck A     153 a.a. 153   X-ray 2.20 Å
  2. 4ovn F,G,H,I,J     146 a.a. 146   X-ray 2.80 Å
  3. 4jq0 D     142 a.a. 142   X-ray 3.84 Å
  4. 2kbi A     97 a.a. 93   NMR  
  5. 4djc B     13 a.a. 11   X-ray 1.35 Å
There are no PDB entries containing fosphenytoin bound to this target protein, although there are 5 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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