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DB01281 : abatacept

Approved biotech drug abatacept ... 2 targets DB01281

Generic name: abatacept
No image
 
Brand name(s): orencia.
Formula: None
IUPAC Formula: None

2
There are 2 target proteins defined in DrugBank for this biotech drug.
 2 
2 of these target proteins have one or more structures in the PDB.
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Target proteins

DrugBank biotech drug Target 1:   UniProt id: P33681 (CD80_HUMAN)  -  T-lymphocyte activation antigen CD80
UniProt id: P33681    287 a.a.  
1. 1dr9 A     200 a.a. 199   X-ray 3.00 Å
  2. 1i8l A,B     199 a.a. 199   X-ray 3.00 Å
There are no PDB entries containing abatacept bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).
DrugBank biotech drug Target 2:   UniProt id: P42081 (CD86_HUMAN)  -  T-lymphocyte activation antigen CD86
UniProt id: P42081    328 a.a.  
1. 1ncn A,B     110 a.a. 109   X-ray 2.70 Å
  2. 1i85 A,B     110 a.a. 109   X-ray 3.20 Å
There are no PDB entries containing abatacept bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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