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DB01227 : levomethadyl acetate

Approved drug levomethadyl acetate ... 3 targets DB01227

Generic name: levomethadyl acetate
 
Brand name(s): orlaam.
Formula: C23H31No2
IUPAC Formula: (3s,6s)-6-(Dimethylamino)-4,4-Diphenylheptan-3-Yl acetate

3
There are 3 target proteins defined in DrugBank for this drug.
 2 
2 of these target proteins have one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P35372 (OPRM_HUMAN)  -  Mu-type opioid receptor
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P30926 (ACHB4_HUMAN)  -  Neuronal acetylcholine receptor subunit beta-4
UniProt id: P30926    497 a.a.  
2asg B,D,E     23 a.a. 23   Theor. model
There are no PDB entries containing levomethadyl acetate bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).
DrugBank drug Target 3:   UniProt id: P32297 (ACHA3_HUMAN)  -  Neuronal acetylcholine receptor subunit alpha-3
UniProt id: P32297    504 a.a.  
2asg A,C     23 a.a. 23   Theor. model
There are no PDB entries containing levomethadyl acetate bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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