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DB01184 : domperidone

Approved drug domperidone ... 2 targets DB01184

Generic name: domperidone
 
Brand name(s): motilium, nauzelin.
Formula: C22H24Cln5O2
IUPAC Formula: 5-Chloro-1-{1-[3-(2-Oxo-2,3-Dihydro-1h-1,3-Benzodiazol-1-Yl)propyl]piperidin-4-Yl}-2,3-Dihydro-1h-
1,3-Benzodiazol-2-One

2
There are 2 target proteins defined in DrugBank for this drug.
 2 
2 of these target proteins have one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P14416 (DRD2_HUMAN)  -  D(2) dopamine receptor
UniProt id: P14416    442 a.a.  
1. 1i15 A     25 a.a. 25   Theor. model
  2. 2you B,C     14 a.a. 13   X-ray 2.19 Å
There are no PDB entries containing domperidone bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: P35462 (DRD3_HUMAN)  -  D(3) dopamine receptor
UniProt id: P35462    400 a.a.  
   more ...
There are no PDB entries containing domperidone bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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