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DB01127 : econazole

Approved drug econazole ... 1 target DB01127

Generic name: econazole PDB Het Group: ECL
 
1 structure in PDB
Brand name(s): econazole nitrate, ecostatin, ecostatin vaginal ovules, ecostatin cream, gyno-pevaryl, gyno-pevaryl 150, ifenec, palavale, pevaryl, spectazole, spectazole cream.
Formula: C18H15Cl3N2O
IUPAC Formula: 1-{2-[(4-Chlorophenyl)methoxy]-2-(2,4-Dichlorophenyl)ethyl}-1h-Imidazole
PDB name: 1-[(2r)-2-[(4-Chlorobenzyl)oxy]-2-(2,4-Dichlorophenyl)ethyl]-1h-Imidazole

1
There is 1 target protein defined in DrugBank for this drug.
 1 
There is 1 PDB structure containing the drug molecule bound to a protein that is not specified as a target.
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Target proteins

DrugBank drug Target 1:   UniProt id: P10613 (CP51_CANAL)  -  Cytochrome P450 51
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:  

 

Other proteins with econazole bound in the PDB

There is 1 "non-target" protein in the PDB containing the econazole molecule bound. That is, the UniProt code for the protein is missing or does not match the drug target above.

Protein 1:   UniProt id: A0R5U2 ()  -  Cytochrome P450 OS=Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) GN=cyp123 PE=1 SV=1
UniProt id: A0R5U2    413 a.a.  
3r9c A   400 a.a. 400   X-ray 2.14 Å
The PDB contains 1 entry of econazole bound to this protein

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Structure selection

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