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DB01104 : sertraline

Approved drug sertraline ... 2 targets DB01104

Generic name: sertraline PDB Het Group: SRE
 
3 structures in PDB
Brand name(s): apo-sertraline, lustral, zoloft.
Formula: C17H17Cl2N
IUPAC Formula: (1s,4s)-4-(3,4-Dichlorophenyl)-N-Methyl-1,2,3,4-Tetrahydronaphthalen-1-Amine
PDB name: (1s,4s)-4-(3,4-Dichlorophenyl)-N-Methyl-1,2,3,4-Tetrahydronaphthalen-1-Amine

2
There are 2 target proteins defined in DrugBank for this drug.
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Target proteins

DrugBank drug Target 1:   UniProt id: P31645 (SC6A4_HUMAN)  -  Sodium-dependent serotonin transporter
UniProt id: P31645    630 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: Q01959 (SC6A3_HUMAN)  -  Sodium-dependent dopamine transporter
UniProt id: Q01959    620 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain

 

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