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DB01101 : capecitabine

Approved drug capecitabine ... 3 targets DB01101

Generic name: capecitabine
 
Brand name(s): xeloda.
Formula: C15H22Fn3O6
IUPAC Formula: Pentyl n-{1-[(2r,3r,4s,5r)-3,4-Dihydroxy-5-Methyloxolan-2-Yl]-5-Fluoro-2-Oxo-1,2-Dihydropyrimidin-4-
Yl}carbamate

3
There are 3 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P04818 (TYSY_HUMAN)  -  Thymidylate synthase
UniProt id: P04818    312 a.a.  
1. 1hvy A,B,C,D     287 a.a. 286   X-ray 1.90 Å
  2. 1ju6 A,B,C,D     286 a.a. 285   X-ray 2.89 Å
  3. 1juj A,B,C,D     286 a.a. 285   X-ray 3.00 Å
  4. 3gg5 A,B,C,D     283 a.a. 283   X-ray 2.77 Å
  5. 3ejl A,B,C,D     283 a.a. 283   X-ray 3.20 Å
   more ...
There are no PDB entries containing capecitabine bound to this target protein, although there are 36 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   Bacterial outer membrane
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   Bacterial outer membrane
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

Structure selection

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