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DB01087 : primaquine

Approved drug primaquine ... 3 targets DB01087

Generic name: primaquine PDB Het Group: 1PQ
 
1 structure in PDB
Brand name(s): neo-quipenyl, primachin.
Formula: C15H21N3O
IUPAC Formula: N-(5-Aminopentan-2-Yl)-6-Methoxyquinolin-8-Amine
PDB name: (4s)-N~4~-(6-Methoxyquinolin-8-Yl)pentane-1,4-Diamine

3
There are 3 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
 1 
There is 1 PDB structure of the drug molecule bound to its target protein.
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Target proteins

DrugBank drug Target 1:   Bacterial outer membrane
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P08729 (K2C7_HUMAN)  -  Keratin, type II cytoskeletal 7
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: P16083 (NQO2_HUMAN)  -  Ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt id: P16083    230 a.a.  
4fgj A,B   230 a.a. 229   X-ray 1.35 Å
The PDB contains 1 entry of primaquine bound to this target protein and 45 entries of this target protein in all (click on orange, plus icon for list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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