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DB01068 : clonazepam

Approved drug clonazepam ... 19 targets DB01068

Generic name: clonazepam
 
Brand name(s): antelepsin, antilepsin, cloazepam, clonopin, iktorivil, klonopin, klonopin rapidly disintegrating, landsen, rivotril.
Formula: C15H10Cln3O3
IUPAC Formula: 5-(2-Chlorophenyl)-7-Nitro-2,3-Dihydro-1h-1,4-Benzodiazepin-2-One

19
There are 19 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P18507 (GBRG2_HUMAN)  -  Gamma-aminobutyric acid receptor subunit gamma-2
UniProt id: P18507    467 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: Q99928 (GBRG3_HUMAN)  -  Gamma-aminobutyric acid receptor subunit gamma-3
UniProt id: Q99928    467 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: O14764 (GBRD_HUMAN)  -  Gamma-aminobutyric acid receptor subunit delta
UniProt id: O14764    452 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 4:   UniProt id: P78334 (GBRE_HUMAN)  -  Gamma-aminobutyric acid receptor subunit epsilon
UniProt id: P78334    506 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 5:   UniProt id: O00591 (GBRP_HUMAN)  -  Gamma-aminobutyric acid receptor subunit pi
UniProt id: O00591    440 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 6:   UniProt id: P24046 (GBRR1_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit rho-1
UniProt id: P24046    479 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 7:   UniProt id: P28476 (GBRR2_HUMAN)  -  Gamma-aminobutyric acid receptor subunit rho-2
UniProt id: P28476    490 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 8:   UniProt id: A8MPY1 (GBRR3_HUMAN)  -  Gamma-aminobutyric acid receptor subunit rho-3
UniProt id: A8MPY1    467 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 9:   UniProt id: Q9UN88 (GBRT_HUMAN)  -  Gamma-aminobutyric acid receptor subunit theta
UniProt id: Q9UN88    632 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 10:   UniProt id: P30536 (TSPOA_HUMAN)  -  Translocator protein
UniProt id: P30536    169 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 11:   UniProt id: P14867 (GBRA1_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit alpha-1
UniProt id: P14867    456 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 12:   UniProt id: P47869 (GBRA2_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit alpha-2
UniProt id: P47869    451 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 13:   UniProt id: P34903 (GBRA3_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit alpha-3
UniProt id: P34903    492 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 14:   UniProt id: P48169 (GBRA4_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit alpha-4
UniProt id: P48169    554 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 15:   UniProt id: P31644 (GBRA5_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit alpha-5
UniProt id: P31644    462 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 16:   UniProt id: P18505 (GBRB1_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit beta-1
UniProt id: P18505    474 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 17:   UniProt id: P47870 (GBRB2_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit beta-2
UniProt id: P47870    512 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 18:   UniProt id: P28472 (GBRB3_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit beta-3
UniProt id: P28472    472 a.a.  
4cof A,B,C,D,E     340 a.a. 309   X-ray 2.97 Å
There are no PDB entries containing clonazepam bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).
DrugBank drug Target 19:   UniProt id: Q8N1C3 (GBRG1_HUMAN)  -  Gamma-aminobutyric acid receptor subunit gamma-1
UniProt id: Q8N1C3    465 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

 

 

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