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DB01058 : praziquantel

Approved drug praziquantel ... 1 target DB01058

Generic name: praziquantel PDB Het Group: PZQ
 
1 structure in PDB
Brand name(s): biltricide.
Formula: C19H24N2O2
IUPAC Formula: 2-Cyclohexanecarbonyl-1h,2h,3h,4h,6h,7h,11bh-Piperazino[2,1-A]isoquinolin-4-One
PDB name: Praziquantel

1
There is 1 target protein defined in DrugBank for this drug.
 1 
There is 1 PDB structure containing the drug molecule bound to a protein that is not specified as a target.
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Target proteins

DrugBank drug Target 1:   Bacterial outer membrane
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:  

 

Other proteins with praziquantel bound in the PDB

There is 1 "non-target" protein in the PDB containing the praziquantel molecule bound. That is, the UniProt code for the protein is missing or does not match the drug target above.

Protein 1:   UniProt id: P08515 ()  -  Glutathione S-transferase class-mu 26 kDa isozyme OS=Schistosoma japonicum PE=1 SV=3
UniProt id: P08515    217 a.a.  
1gtb A   218 a.a. 217   X-ray 2.60 Å
The PDB contains 1 entry of praziquantel bound to this protein

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Structure selection

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