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DB01006 : letrozole

Approved drug letrozole ... 1 target DB01006

Generic name: letrozole
 
Brand name(s): femara.
Formula: C17H11N5
IUPAC Formula: 4-[(4-Cyanophenyl)(1h-1,2,4-Triazol-1-Yl)methyl]benzonitrile

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P11511 (CP19A_HUMAN)  -  Cytochrome P450 19A1
UniProt id: P11511    502 a.a.  
1. 3s79 A     452 a.a. 452   X-ray 2.75 Å
  2. 3eqm A     452 a.a. 452   X-ray 2.90 Å
  3. 3s7s A     452 a.a. 452   X-ray 3.21 Å
  4. 4kq8 A     452 a.a. 452   X-ray 3.29 Å
  5. 4gl5 A     452 a.a. 452   X-ray 3.48 Å
   more ...
There are no PDB entries containing letrozole bound to this target protein, although there are 7 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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