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DB00949 : felbamate

Approved drug felbamate ... 3 targets DB00949

Generic name: felbamate
 
Brand name(s): felbamyl, felbatol, taloxa.
Formula: C11H14N2O4
IUPAC Formula: 3-(Carbamoyloxy)-2-Phenylpropyl carbamate

3
There are 3 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: Q13224 (NMDE2_HUMAN)  -  Glutamate [NMDA] receptor subunit epsilon-2
UniProt id: Q13224    1483 a.a.  
1. 1s11 A     141 a.a. 141   Theor. model
  2. 1s2s A     139 a.a. 139   Theor. model
There are no PDB entries containing felbamate bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: Q8TCU5 (NMD3A_HUMAN)  -  Glutamate [NMDA] receptor subunit 3A
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: Q12879 (NMDE1_HUMAN)  -  Glutamate [NMDA] receptor subunit epsilon-1
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

 

 

Structure selection

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