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DB00860 : prednisolone

Approved drug prednisolone ... 1 target DB00860

Generic name: prednisolone
 
Brand name(s): ak-pred, ak-tate, alphadrol, articulose-50, co-hydeltra, codelcortone, cordrol, cortalone, cotogesic, cotolone, decaprednil, decortin h, delcortol, delta f, delta-cortef, delta-stab, deltacortenol, deltacortril, deltacortril enteric, deltasolone, deltisilone, depo-medrol, derpo pd, dexa-cortidelt hostacortin h, di-adreson f, dicortol, donisolone, dydeltrone, eazolin d, econopred, erbacort, erbasona, estilsona, fernisolone, fernisolone p, fernisolone-p, flamasone, hostacortin h, hydeltra, hydeltra-tba, hydeltrasol, hydeltrone, hydrodeltalone, hydrodeltisone, hydroretrocortin, hydroretrocortine, i-pred, inflamase forte, inflamase mild, key-pred, klismacort, lentosone, lite pred, m-predrol, medrol, medrol acetate, metacortandralone, meti-derm, meticortelone, metreton, nor-pred t.b.a., ocu-pred, ocu-pred forte, ophtho-tate, orapred, panafcortelone, paracortol, paracotol, pediapred, precortalon, precortancyl, precortilon, precortisyl, pred forte, pred mild, predair, predair a, predair forte, predalone t.b.a., predate tba, predate-50, predcor-25, predcor-50, predcor-tba, predne-dome, prednelan, predni-dome, prednicen, predniliderm, predniretard, prednis, predonin, predonine, prelone, prenolone, rolisone, scherisolon, solone, steran, sterane, sterolone, supercortisol, ulacort, ultra pred, ultracorten h, ultracortene h, ultracortene-h, ultracortene-hydrogen.
Formula: C21H28O5
IUPAC Formula: (1s,2r,10s,11s,14r,15s,17s)-14,17-Dihydroxy-14-(2-Hydroxyacetyl)-2,15-
Dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-Dien-5-One

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
Links  
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Target proteins

DrugBank drug Target 1:   UniProt id: P04150 (GCR_HUMAN)  -  Glucocorticoid receptor
UniProt id: P04150    776 a.a.  
1. 1m2z A,D     255 a.a. 254   X-ray 2.50 Å
  2. 3bqd A     253 a.a. 252   X-ray 2.50 Å
  3. 3k22 A,B     250 a.a. 248   X-ray 2.10 Å
  4. 3e7c A,B     248 a.a. 246   X-ray 2.15 Å
  5. 4p6w A     252 a.a. 245   X-ray 1.95 Å
   more ...
There are no PDB entries containing prednisolone bound to this target protein, although there are 15 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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