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DB00825 : menthol

Approved drug menthol ... 4 targets DB00825

Generic name: menthol
 
Brand name(s): none.
Formula: C10H20O
IUPAC Formula: (1r,2s,5r)-5-Methyl-2-(Propan-2-Yl)cyclohexan-1-Ol

4
There are 4 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
Links  
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ChEBI
KEGG drug
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Target proteins

DrugBank drug Target 1:   UniProt id: Q7Z2W7 (TRPM8_HUMAN)  -  Transient receptor potential cation channel subfamily M member 8
UniProt id: Q7Z2W7    1104 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: O75762 (TRPA1_HUMAN)  -  Transient receptor potential cation channel subfamily A member 1
UniProt id: O75762    1119 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: Q8NET8 (TRPV3_HUMAN)  -  Transient receptor potential cation channel subfamily V member 3
UniProt id: Q8NET8    790 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 4:   UniProt id: P41145 (OPRK_HUMAN)  -  Kappa-type opioid receptor
UniProt id: P41145    379 a.a.  
2a0d A     380 a.a. 378   Theor. model
There are no PDB entries containing menthol bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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