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DB00797 : tolazoline

Approved drug tolazoline ... 3 targets DB00797

Generic name: tolazoline
 
Brand name(s): artonil, benzazoline, benzidazol, benzolin, benzylimidazoline, dilatol asi, divascol, imidalin, imidaline, kasimid, lambril, olitensol, peripherine, phenylmethylimidazoline, prefaxil, priscol, priscoline, tolazolin, vasimid, vasodil, vasodilatan.
Formula: C10H12N2
IUPAC Formula: 2-Benzyl-4,5-Dihydro-1h-Imidazole

3
There are 3 target proteins defined in DrugBank for this drug.
 2 
2 of these target proteins have one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P35348 (ADA1A_HUMAN)  -  Alpha-1A adrenergic receptor
UniProt id: P35348    466 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P08913 (ADA2A_HUMAN)  -  Alpha-2A adrenergic receptor
UniProt id: P08913    449 a.a.  
1. 1hll A     32 a.a. 32   NMR  
  2. 1hof A     32 a.a. 32   NMR  
  3. 1ho9 A     32 a.a. 31   NMR  
  4. 1hod A     32 a.a. 31   NMR  
There are no PDB entries containing tolazoline bound to this target protein, although there are 4 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 3:   UniProt id: P35367 (HRH1_HUMAN)  -  Histamine H1 receptor
UniProt id: P35367    487 a.a.  
   more ...
There are no PDB entries containing tolazoline bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

 

 

Structure selection

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