spacer
spacer

Search 

DB00765 : metyrosine

Approved drug metyrosine ... 1 target DB00765

Generic name: metyrosine
 
Brand name(s): demser.
Formula: C10H13No3
IUPAC Formula: (2s)-2-Amino-3-(4-Hydroxyphenyl)-2-Methylpropanoic acid

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
Links  
DrugBank
RxList
KEGG drug
PubChem
Information  
Pharmacology
Indication
Action

 

Target proteins

DrugBank drug Target 1:   UniProt id: P07101 (TY3H_HUMAN)  -  Tyrosine 3-monooxygenase
UniProt id: P07101    527 a.a.  
2xsn A,B,C,D     335 a.a. 334   X-ray 2.68 Å
There are no PDB entries containing metyrosine bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

Use the checkboxes above to select the structure(s) of interest, and then press the required button below to view:
View 3D structure
Select preferred viewer and click on 3D struct button
AstexViewer™@MSD-EBI
RasMol
STRAP multiple alignment viewer
LIGPLOT diagrams
Press button below for LIGPLOT diagrams of drug-protein interactions in all selected structures above.

  spacer

spacer