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DB00716 : nedocromil

Approved drug nedocromil ... 5 targets DB00716

Generic name: nedocromil
 
Brand name(s): alocril, nedocromil [usan:ban:inn], nedocromilo [spanish], nedocromilum [latin], tilade.
Formula: C19H17No7
IUPAC Formula: 9-Ethyl-4,6-Dioxo-10-Propyl-4h,6h,9h-Chromeno[7,6-B]pyridine-2,8-Dicarboxylic acid

5
There are 5 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: Q9Y271 (CLTR1_HUMAN)  -  Cysteinyl leukotriene receptor 1
UniProt id: Q9Y271    337 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: Q9NS75 (CLTR2_HUMAN)  -  Cysteinyl leukotriene receptor 2
UniProt id: Q9NS75    346 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: P21462 (FPR1_HUMAN)  -  FMet-Leu-Phe receptor
UniProt id: P21462    350 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 4:   UniProt id: Q13258 (PD2R_HUMAN)  -  Prostaglandin D2 receptor
UniProt id: Q13258    359 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 5:   UniProt id: P07900 (HS90A_HUMAN)  -  Heat shock protein HSP 90-alpha
UniProt id: P07900    731 a.a.  
1. 3q6m A,B,C     372 a.a. 372   X-ray 3.00 Å
  2. 3q6n A,B,C,D,...     360 a.a. 360   X-ray 3.05 Å
  3. 2xjx A     221 a.a. 221   X-ray 1.66 Å
  4. 4egi A     218 a.a. 218   X-ray 1.79 Å
  5. 3r4p A,B     222 a.a. 217   X-ray 1.70 Å
   more ...
There are no PDB entries containing nedocromil bound to this target protein, although there are 188 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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