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DB00711 : diethylcarbamazine

Approved drug diethylcarbamazine ... 2 targets DB00711

Generic name: diethylcarbamazine
 
Brand name(s): bitirazine, caracide, caricide, cypip, decacide, hetrazan, notezine, spatonin.
Formula: C10H21N3O
IUPAC Formula: N,N-Diethyl-4-Methylpiperazine-1-Carboxamide

2
There are 2 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
Links  
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KEGG drug
PubChem
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Target proteins

DrugBank drug Target 1:   UniProt id: P09917 (LOX5_HUMAN)  -  Arachidonate 5-lipoxygenase
UniProt id: P09917    673 a.a.  
1. 2abv A     673 a.a. 673   Theor. model
  2. 3o8y A,B     676 a.a. 658   X-ray 2.39 Å
  3. 3v92 B,A     670 a.a. 658   X-ray 2.74 Å
  4. 3v98 A,B     669 a.a. 657   X-ray 2.07 Å
  5. 3v99 A,B     630 a.a. 618   X-ray 2.25 Å
There are no PDB entries containing diethylcarbamazine bound to this target protein, although there are 5 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: P23219 (PGH1_HUMAN)  -  Prostaglandin G/H synthase 1
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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