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DB00705 : delavirdine

Approved drug delavirdine ... 1 target DB00705

Generic name: delavirdine PDB Het Group: SPP
 
1 structure in PDB
Brand name(s): rescriptor.
Formula: C22H28N6O3S
IUPAC Formula: N-{2-[(4-{3-[(Propan-2-Yl)amino]pyridin-2-Yl}piperazin-1-Yl)carbonyl]-1h-Indol-5-
Yl}methanesulfonamide
PDB name: (1-(5-Methansulphonamido-1h-Indol-2-Yl-Carbonyl)4-[Methylamino)pyridinyl]piperazine

1
There is 1 target protein defined in DrugBank for this drug.
 1 
There is 1 PDB structure containing the drug molecule bound to a protein that is not specified as a target.
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Target proteins

DrugBank drug Target 1:   UniProt id: Q5DNL9 (Q5DNL9_9HIV1)  -  Reverse transcriptase
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:  

 

Other proteins with delavirdine bound in the PDB

There is 1 "non-target" protein in the PDB containing the delavirdine molecule bound. That is, the UniProt code for the protein is missing or does not match the drug target above.

Protein 1:   UniProt id: P04585 ()  -  Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) GN=gag-pol PE=1 SV=4
UniProt id: P04585    1434 a.a.  
1klm A   537 a.a. 536   X-ray 2.65 Å
The PDB contains 1 entry of delavirdine bound to this protein

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Structure selection

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