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DB00700 : eplerenone

Approved drug eplerenone ... 1 target DB00700

Generic name: eplerenone
 
Brand name(s): inspra.
Formula: C24H30O6
IUPAC Formula: Methyl (1'R,2r,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-Dimethyl-5,5'-Dioxo-18'-Oxaspiro[oxolane-2,14'-
Pentacyclo[8.8.0.0^{1,17}.0^{2,7}.0^{11,15}]octadecan]-6'-Ene-9'-Carboxylate

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
Links  
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Information  
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Target proteins

DrugBank drug Target 1:   UniProt id: P08235 (MCR_HUMAN)  -  Mineralocorticoid receptor
UniProt id: P08235    983 a.a.  
1. 2aax A,B     261 a.a. 259   X-ray 1.75 Å
  2. 2aa6 A,B     260 a.a. 258   X-ray 1.95 Å
  3. 2ab2 A,B     259 a.a. 257   X-ray 1.85 Å
  4. 3wff A     258 a.a. 255   X-ray 2.05 Å
  5. 2aa5 A,B     255 a.a. 254   X-ray 2.20 Å
   more ...
There are no PDB entries containing eplerenone bound to this target protein, although there are 15 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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