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DB00692 : phentolamine

Approved drug phentolamine ... 2 targets DB00692

Generic name: phentolamine
 
Brand name(s): phenotolamine, phentalamine, phentolamine mesilate, phentolamine mesylate, phentolamine mesylate [usan], phentolamine methanesulfonate, phentolamine methanesulphonate, phentolamine, methyl sulfonate, regitin, regitin methanesulphonate, regitine, regitine mesylate, regitine methanesulfonate, regitipe, rogitine.
Formula: C17H19N3O
IUPAC Formula: 3-[(4,5-Dihydro-1h-Imidazol-2-Ylmethyl)(4-Methylphenyl)amino]phenol

2
There are 2 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P08913 (ADA2A_HUMAN)  -  Alpha-2A adrenergic receptor
UniProt id: P08913    449 a.a.  
1. 1hll A     32 a.a. 32   NMR  
  2. 1hof A     32 a.a. 32   NMR  
  3. 1ho9 A     32 a.a. 31   NMR  
  4. 1hod A     32 a.a. 31   NMR  
There are no PDB entries containing phentolamine bound to this target protein, although there are 4 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: P35348 (ADA1A_HUMAN)  -  Alpha-1A adrenergic receptor
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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