spacer
spacer

Search 

DB00671 : cefixime

Approved drug cefixime ... 1 target DB00671

Generic name: cefixime PDB Het Group: C04
 
1 structure in PDB
Brand name(s): cfix, cefixoral, cefspan, cephoral, oroken, suprax, unixime.
Formula: C16H15N5O7S2
IUPAC Formula: (6r,7r)-7-[(2z)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-[(Carboxymethoxy)imino]acetamido]-3-Ethenyl-8-Oxo-5-
Thia-1-Azabicyclo[4.2.0]oct-2-Ene-2-Carboxylic acid
PDB name: (6r,7r)-7-({(2z)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-[(Carboxymethoxy)imino]acetyl}amino)-3-Ethenyl-8-
Oxo-5-Thia-1-Azabicyclo[4.2.0]oct-2-Ene-2-Carboxylic acid

1
There is 1 target protein defined in DrugBank for this drug.
 1 
There is 1 PDB structure containing the drug molecule bound to a protein that is not specified as a target.
Links  
DrugBank
RxList
ChEBI
KEGG drug
PubChem
MSDChem
Ligand Expo
HIC-Up
Information  
Pharmacology
Indication
Action

 

Target proteins

DrugBank drug Target 1:   UniProt id: P44469 (PBP2_HAEIN)  -  Penicillin-binding protein 2
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:  

 

Other proteins with cefixime bound in the PDB

There is 1 "non-target" protein in the PDB containing the cefixime molecule bound. That is, the UniProt code for the protein is missing or does not match the drug target above.

Protein 1:   UniProt id: Q9HV14 ()  -  Uncharacterized protein OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=PA4794 PE=1 SV=1
UniProt id: Q9HV14    159 a.a.  
4kou A   159 a.a. 158   X-ray 1.60 Å
The PDB contains 1 entry of cefixime bound to this protein

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Structure selection

Use the checkboxes above to select the structure(s) of interest, and then press the required button below to view:
View 3D structure
Select preferred viewer and click on 3D struct button
AstexViewer™@MSD-EBI
RasMol
STRAP multiple alignment viewer
LIGPLOT diagrams
Press button below for LIGPLOT diagrams of drug-protein interactions in all selected structures above.

  spacer

spacer