spacer
spacer

Search 

DB00611 : butorphanol

Approved drug butorphanol ... 3 targets DB00611

Generic name: butorphanol
 
Brand name(s): beforal, moradol, stadol, stadol ns.
Formula: C21H29No2
IUPAC Formula: (1s,9r,10s)-17-(Cyclobutylmethyl)-17-Azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-Triene-
4,10-Diol

3
There are 3 target proteins defined in DrugBank for this drug.
 2 
2 of these target proteins have one or more structures in the PDB.
Links  
DrugBank
RxList
ChEBI
KEGG drug
PubChem
Information  
Pharmacology
Indication
Action

 

Target proteins

DrugBank drug Target 1:   UniProt id: P41145 (OPRK_HUMAN)  -  Kappa-type opioid receptor
UniProt id: P41145    379 a.a.  
2a0d A     380 a.a. 378   Theor. model
There are no PDB entries containing butorphanol bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: P41143 (OPRD_HUMAN)  -  Delta-type opioid receptor
UniProt id: P41143    371 a.a.  
1ozc A     268 a.a. 268   Theor. model
There are no PDB entries containing butorphanol bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 3:   UniProt id: P35372 (OPRM_HUMAN)  -  Mu-type opioid receptor
UniProt id: P35372    400 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

Structure selection

Use the checkboxes above to select the structure(s) of interest, and then press the required button below to view:
View 3D structure
Select preferred viewer and click on 3D struct button
AstexViewer™@MSD-EBI
RasMol
STRAP multiple alignment viewer

  spacer

spacer