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DB00592 : piperazine

Approved drug piperazine ... 1 target DB00592

Generic name: piperazine PDB Het Group: PZE
 
1 structure in PDB
Brand name(s): anatensol, antepar, antiren, asca-trol no. 3, dapotum, dispermine, eraverm, lumbrical, moditen, multifuge, omca, pacinol, permitil, piperazidine, pipersol, tasnon, tensofin, upixon, uvilon, vermex, vermidol, vermizine, worm-a-ton, worm-away, wurmirazin.
Formula: C4H10N2
IUPAC Formula: Piperazine
PDB name: Piperazine

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
 1 
There is 1 PDB structure containing the drug molecule bound to a protein that is not specified as a target.
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Target proteins

DrugBank drug Target 1:   UniProt id: P28472 (GBRB3_HUMAN)  -  Gamma-aminobutyric-acid receptor subunit beta-3
UniProt id: P28472    472 a.a.  
4cof A,B,C,D,E     340 a.a. 309   X-ray 2.97 Å
There are no PDB entries containing piperazine bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Other proteins with piperazine bound in the PDB

There is 1 "non-target" protein in the PDB containing the piperazine molecule bound. That is, the UniProt code for the protein is missing or does not match the drug target above.

Protein 1:   UniProt id: A3F9D6 ()  -  Lactoperoxidase OS=Capra hircus GN=LPO PE=1 SV=1
UniProt id: A3F9D6    711 a.a.  
3qf1 A   594 a.a. 593   X-ray 2.60 Å
The PDB contains 1 entry of piperazine bound to this protein

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Structure selection

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