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DB00564 : carbamazepine

Approved drug carbamazepine ... 1 target DB00564

Generic name: carbamazepine
 
Brand name(s): apo-carbamazepine, atretol, biston, calepsin, carbamazepen, carbatrol, carbazepine, carbelan, epitol, equetro, finlepsin, karbamazepin, lexin, neurotol, novo-carbamaz, nu-carbamazepine, sirtal, stazepin, stazepine, taro-carbamazepine, taro-carbamazepine cr, tegretal, tegretol, tegretol chewtabs, tegretol cr, tegretol-xr, telesmin, teril, timonil.
Formula: C15H12N2O
IUPAC Formula: 2-Azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-Heptaene-2-Carboxamide

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
Links  
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RxList
ChEBI
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Information  
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Target proteins

DrugBank drug Target 1:   UniProt id: Q14524 (SCN5A_HUMAN)  -  Sodium channel protein type 5 subunit alpha
UniProt id: Q14524    2015 a.a.  
1. 4dck A     153 a.a. 153   X-ray 2.20 Å
  2. 4jq0 D     142 a.a. 142   X-ray 3.84 Å
  3. 2kbi A     97 a.a. 93   NMR  
  4. 2l53 B     31 a.a. 27   NMR  
  5. 4djc B     13 a.a. 11   X-ray 1.35 Å
There are no PDB entries containing carbamazepine bound to this target protein, although there are 5 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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